A Nationwide, Population-Based Cohort Study

Ellen Moseholm; Terese Lea Katzenstein; Gitte Pedersen; Isik Somuncu Johansen; Lisa Skyggelund Wienecke; Merete Storgaard; Niels Obel; Nina Weis

HIV Medicine. 2022;23(9):1007-1018. 

Antiretroviral therapy (ART) is recommended worldwide for all people with HIV, including pregnant women.[1] As a result, an increasing number of women living with HIV (WLWH) will either conceive or start treatment during pregnancy. The success of ART in combination with changing recommendations has resulted in a decreased risk of perinatal transmission to < 1% in Denmark and other high-income countries,[2,3] leading to a growing population of HIV-exposed, uninfected (HEU) children.[4] From a treatment perspective, pregnant women are a special population, largely because of the opportunity to prevent perinatal transmission of HIV and the need to consider the safety of the women themselves and their exposed foetuses and children.[5]